Using 'Omic and Digital Technologies Toward Better Fasciolosis Control

Chromatin accessibility landscape of a parasitic nematode during embryogenesis

H Lu, T Campos, SB Sumanam, T Wang, Y Zheng, RB Gasser, ND Young

2026-12-01

Background: Chromatin accessibility is a fundamental determinant of genome regulation, enabling transcription factors and RNA poly..

Chromosome-scale nuclear genome and proteome of Anoplocephala perfoliata elucidate lineage-specific features of a ‘neglected’ equine tapeworm

ND Young, T Wang, CS Ang, D Lale, HP Fuehrer, SB Sumanam, PK Korhonen, BCH Chang, RB Gasser

2026-12-01

Background: Anoplocephala perfoliata is the most prevalent and pathogenic tapeworm (cestode) of horses worldwide, yet it remains m..

Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus

Y Shen, ND Young, J Song, BE Sleebs, BCH Chang, EF Lee, WD Fairlie, RB Gasser

2026-12-01

Background: Programmed cell death (or apoptosis) is a fundamental process in metazoans, extensively characterised in mammals and o..

Intrinsic apoptosis in nematodes: Evolutionary plasticity and biotechnological opportunities

M Kaethner, ND Young, EF Lee, WD Fairlie, BE Sleebs, BCH Chang, RB Gasser

2026-09-01

Intrinsic apoptosis is a form of programmed cell death that underpins development, tissue homeostasis and stress responses across ..

High-resolution climate modelling of fasciolosis risk in Australia: A One Health early-warning framework

RM Athar Ali, MA Stevenson, L Tyrell, NED Calvani, T Beddoe, G Rawlin, T Spithill, ND Young, A Jabbar

2026-06-01

Fasciolosis, caused by the liver fluke Fasciola hepatica, is a climate-sensitive parasitic disease that threatens livestock health..

A practical miracidial motility assay for assessing Fasciola hepatica sensitivity to compounds in vitro

M Zheng, AC Taki, T Sukee, J Hodgkinson, TW Spithill, RB Gasser, ND Young

2026-04-01

Fasciola hepatica causes fasciolosis in livestock and humans worldwide, yet reliable tools to assess drug efficacy against the ear..